CoProjects is the funding mechanism for ImmunoX projects; CoLabs is the technology and infrastructure that supports the CoProjects. CoLabs is funded by institutional support and serves a user base across the entire UCSF community, not just the CoProjects.
Unlike fragmented “cores,” which age and become obsolete over time, CoLabs revitalizes the model for central lab resources by capitalizing on critical personnel and cutting-edge technologies, and driving collaboration across disciplines.
The model will house all CoLabs in a contiguous space and create a set of common pipelines and workflows in one centralized locale. It will recruit and retain world-class staff through project engagement, backstopped “tenure,” and annual operational funds. And it will develop and invest in transformative methods and technologies.
In its current form, CoLabs consolidates three existing groups and establishes two new ones under one roof:
Disease to Biology CoLab: A new CoLab that specializes in consistent and high-quality human specimen processing. Technicians associated with ImmunoX CoProjects are housed here and are responsible for coordinating specimen processing and data analysis workflows with other CoLabs.
Flow Cytometry CoLab: A CoLab that integrates the existing Parnassus Flow Cytometry Core and specializes in counting, sorting, and analyzing suspensions of cells using advanced cell sorting and cytometric analyses technologies.
Biological Imaging Development CoLab: A CoLab that integrates the existing Biological Imaging Development Center and specializes in assembling, testing, and applying emerging light microscopy techniques and technologies.
Genomics CoLab: A Colab that integrates existing but fragmented units at UCSF. It specializes in performing single-cell gene transcript sequencing and developing and deploying innovative methods for analyzing and modifying gene function.
Data Sciences CoLab: A new CoLab to develop bioinformatic frameworks for curating, storing, analyzing, and sharing access to data produced through the CoLabs pipeline. It will also house bioinformaticians and computational biologists to drive ImmunoX CoProjects.